Data directory structure

The structure of data directory and convention of files naming will follow the BIDS specification (v1.5.0-dev).

Participants and sessions

The participants.tsv for each BIDS pipeline has a number of extra columns beyond participant_id. These have the following meaning:

Field Meaning
sex Male / Female
birth_age Gestational age at birth in weeks
birth_weight Birthweight (kg)
singleton Singleton pregnancy (S) / Multiple pregnancy (M)

The sessions.tsv file has extra columns beyond session_id. These have the following meaning:

Field Meaning
scan_age Gestational age at scan in weeks
scan_head_circumference Head circumference (cm)
radiology_score Subject status, see below
scan_number 1 for the first scan, 2 for the second
sedation 1 if the subject was sedated during the scan, 0 otherwise

The MRI scans were reviewed by a specialist perinatal neuroradiologist who scored each subject using the following scale:

  1. Normal appearance for age

  2. Incidental findings with unlikely significance for clinical outcome or analysis (e.g. subdural haemorrhage. Isolated subependymal cysts. Mild inferior vermis rotation)

  3. Incidental findings with unlikely clinical significance but possible analysis significance (e.g. several punctate lesions or other focal white matter / cortical lesions not thought to be of clinical significance)

  4. Incidental findings with possible clinical significance. Unlikely analysis significance (e.g. Isolated non brain anomaly for example in pituitary / on tongue)

  5. Incidental finding with possible / likely significance for both clinical and imaging analysis (e.g. Major lesions within white matter cortex, cerebellum and or basal ganglia; small head / brain < 1st centile)

  6. Q, meaning poor quality anatomical data

Image Spaces

Images are released in their own native image space with no correspondence to other images (within or across subjects). Transforms (affine and warps) are provided to align images within subjects and to a common space.

Transform filenames contain a from key and a to key to indicate the direction of the transform. The from value is the space-label for the origin/source/moving image, and the to value is the space-label for the reference/target image.

Volumetric transforms have the key-value mode-image, whereas surface transforms have the key-value mode-sphere.

Non-linear volumetric transforms are FSL format with the extension .nii.gz, rigid/affine volumetric transforms have the extension .mat, and surface transforms have the extension .surf.gii.

Examples:

# volumetric affine transform
xfm/sub-{subid}_ses-{sesid}_from-{space-label}_to-{space-label}_mode-image.mat

# volumetric nonlinear transform
xfm/sub-{subid}_ses-{sesid}_from-{space-label}_to-{space-label}_mode-image.nii.gz 

# surface transform
xfm/sub-{subid}_ses-{sesid}_hemi-{hemi}_from-{space-label}_to-{space-label}_dens-32k_mode-sphere.surf.gii 

Space labels:

Label Description
dhcp{age}wk Schuh et al. (2018) dHCP atlas week-{age} volumetric template space
extdhcp{age}wk Schuh et al. (2018) dHCP extended atlas week-{age} volumetric template space
serag{age}wk Serag et al. (2012) atlas week-{age} volumetric template space
dhcpSym{age} Bozek et al. (2018) dHCP symmetric surface atlas week-{age}
T2w native structural T2w space (per subject)
bold motion and distortion corrected functional space (per subject)
dwi motion and distortion corrected diffusion space (per subject)

Reconstruction Pipeline

Path: rawdata/sub-{subid}/ses-{sesid}

Group Description Filename
T1 T1w magnitude image (native acquired stack) anat/sub-{subid}_ses-{sesid}_run-{seqnum}_T1w.nii
T1 T1w phase image (native acquired stack) anat/sub-{subid}_ses-{sesid}_run-{seqnum}_rec-phase_T1w.nii
T1 T1w magnitude image (motion corrected and super resolved) anat/sub-{subid}_ses-{sesid}_run-{seqnum}_rec-mcsr_T1w.nii
T1 T1w phase image (motion corrected and super resolved) anat/sub-{subid}_ses-{sesid}_run-{seqnum}_rec-mcsrphase_T1w.nii
T1 T1w magnitude image (motion corrected) anat/sub-{subid}_ses-{sesid}_run-{seqnum}_rec-mc_T1w.nii
T1 T1w phase image (motion corrected) anat/sub-{subid}_ses-{sesid}_run-{seqnum}_rec-mcphase_T1w.nii
T1 T1w image (combined Slice-to-Volume reconstruction) anat/sub-{subid}_ses-{sesid}_rec-SVR_T1w.nii
T2 T2w magnitude image (native acquired stack) anat/sub-{subid}_ses-{sesid}_run-{seqnum}_T2w.nii
T2 T2w phase image (native acquired stack) anat/sub-{subid}_ses-{sesid}_run-{seqnum}_rec-phase_T2w.nii
T2 T2w magnitude image (motion corrected and super resolved) anat/sub-{subid}_ses-{sesid}_run-{seqnum}_rec-mcsr_T2w.nii
T2 T2w phase image (motion corrected and super resolved) anat/sub-{subid}_ses-{sesid}_run-{seqnum}_rec-mcsrphase_T2w.nii
T2 T2w magnitude image (motion corrected) anat/sub-{subid}_ses-{sesid}_run-{seqnum}_rec-mc_T2w.nii
T2 T2w phase image (motion corrected) anat/sub-{subid}_ses-{sesid}_run-{seqnum}_rec-mcphase_T2w.nii
T2 T2w image (combined Slice-to-Volume reconstruction) anat/sub-{subid}_ses-{sesid}_rec-SVR_T2w.nii
T13D T1w magnitude image (3D MPRAGE) anat/sub-{subid}_ses-{sesid}_run-{seqnum}_acq-MPRAGE_T1w.nii
T13D T1w phase image (3D MPRAGE) anat/sub-{subid}_ses-{sesid}_run-{seqnum}_acq-MPRAGE_rec-phase_T1w.nii
dMRI Single-band Ref (magnitude) dwi/sub-{subid}_ses-{sesid}_run-{seqnum}_sbref.nii
dMRI Single-band Ref (phase) dwi/sub-{subid}_ses-{sesid}_run-{seqnum}_rec-phase_sbref.nii
dMRI Multi-band dMRI EPI (magnitude) dwi/sub-{subid}_ses-{sesid}_run-{seqnum}_dwi.nii
dMRI Multi-band dMRI EPI (phase) dwi/sub-{subid}_ses-{sesid}_run-{seqnum}_rec-phase_dwi.nii
dMRI Multi-band dMRI EPI (denoised magnitude) dwi/sub-{subid}_ses-{sesid}_run-{seqnum}_rec-denoised_dwi.nii
dMRI Multi-band dMRI EPI (denoised phase) dwi/sub-{subid}_ses-{sesid}_run-{seqnum}_rec-denoisedphase_dwi.nii
dMRI Multi-band dMRI EPI (Chi2-maps) dwi/sub-{subid}_ses-{sesid}_run-{seqnum}_rec-chi2_dwi.nii
dMRI Estimate of error in denoised data dwi/sub-{subid}_ses-{sesid}_run-{seqnum}_rec-denoisederror_dwi.nii
fMRI Single-band Ref (magnitude) func/sub-{subid}_ses-{sesid}_run-{seqnum}_task-rest_sbref.nii
fMRI Single-band Ref (phase) func/sub-{subid}_ses-{sesid}_run-{seqnum}_task-rest_rec-phase_sbref.nii
fMRI Resting fMRI (magnitude) func/sub-{subid}_ses-{sesid}_run-{seqnum}_task-rest_bold.nii
fMRI Resting fMRI (phase) func/sub-{subid}_ses-{sesid}_run-{seqnum}_task-rest_phase.nii
fMRI 4D Spin Echo EPI with different phase encode directions (for topup fieldmap estimation) fmap/sub-{subid}_ses-{sesid}_run-{seqnum}_epi.nii
fMRI 4D Spin Echo EPI (phase) fmap/sub-{subid}_ses-{sesid}_run-{seqnum}_rec-phase_epi.nii
B0 Dual echo-time (magnitude) fmap/sub-{subid}_ses-{sesid}_run-{seqnum}_magnitude.nii
B0 Dual echo-time (phase) fmap/sub-{subid}_ses-{sesid}_run-{seqnum}_phase.nii
B0 B0 field map (Hz) - filtered and smoothed fmap/sub-{subid}_ses-{sesid}_run-{seqnum}_rec-filtered_fieldmap.nii
B0 B0 field map (Hz) - unfiltered fmap/sub-{subid}_ses-{sesid}_run-{seqnum}_rec-raw_fieldmap.nii
B1 DREAM (magnitude) B1/sub-{subid}_ses-{sesid}_run-{seqnum}_magnitude.nii
B1 DREAM (phase) B1/sub-{subid}_ses-{sesid}_run-{seqnum}_phase.nii
B1 B1+ field map (rel. nom. flip) B1/sub-{subid}_ses-{sesid}_run-{seqnum}_b1map.nii
recon03 Multi-band dMRI EPI - release 2 reconstruction dwi/sub-{subid}_ses-{sesid}_rec-release2_dwi.nii

Path: sourcedata/sub-{subid}/ses-{sesid}

Group Description Filename
fMRI Resting fMRI Physlog (uncropped) func/sub-{subid}_ses-{sesid}_run-{seqnum}_task-rest_physio.log

Structural pipeline

Path: derivatives/dhcp_anat_pipeline/sub-{subid}/ses-{sesid}

Description Filename
FSL BET brain mask anat/sub-{subid}_ses-{sesid}_desc-brain_mask.nii.gz
Draw-EM regional segmentation (87 labels) anat/sub-{subid}_ses-{sesid}_desc-drawem87_dseg.nii.gz
Draw-EM tissue segmentation (9 labels) anat/sub-{subid}_ses-{sesid}_desc-drawem9_dseg.nii.gz
Cortical ribbon anat/sub-{subid}_ses-{sesid}_desc-ribbon_dseg.nii.gz
T1 weighted image (in T2 space) anat/sub-{subid}_ses-{sesid}_T1w.nii.gz
T1 bias field (in T2 space) anat/sub-{subid}_ses-{sesid}_desc-biasfield_T1w.nii.gz
T1 weighted, bias corrected image (in T2 space) anat/sub-{subid}_ses-{sesid}_desc-restore_T1w.nii.gz
T2 weighted image anat/sub-{subid}_ses-{sesid}_T2w.nii.gz
T2 bias field anat/sub-{subid}_ses-{sesid}_desc-biasfield_T2w.nii.gz
T2 weighted, bias corrected image anat/sub-{subid}_ses-{sesid}_desc-restore_T2w.nii.gz
QC report sub-{subid}_ses-{sesid}_qc.pdf
Left/Right white surface anat/sub-{subid}_ses-{sesid}_hemi-{hemi}_wm.surf.gii
Left/Right pial surface anat/sub-{subid}_ses-{sesid}_hemi-{hemi}_pial.surf.gii
Left/Right mid-thickness surface anat/sub-{subid}_ses-{sesid}_hemi-{hemi}_midthickness.surf.gii
Left/Right inflated surface anat/sub-{subid}_ses-{sesid}_hemi-{hemi}_inflated.surf.gii
Left/Right very inflated surface anat/sub-{subid}_ses-{sesid}_hemi-{hemi}_vinflated.surf.gii
Left/Right spherical surface anat/sub-{subid}_ses-{sesid}_hemi-{hemi}_sphere.surf.gii
Cortical curvature anat/sub-{subid}_ses-{sesid}_curv.dscalar.nii
Left/Right cortical curvature anat/sub-{subid}_ses-{sesid}_hemi-{hemi}_curv.shape.gii
Sulcal depth anat/sub-{subid}_ses-{sesid}_sulc.dscalar.nii
Left/Right sulcal depth anat/sub-{subid}_ses-{sesid}_hemi-{hemi}_sulc.shape.gii
Cortical thickness anat/sub-{subid}_ses-{sesid}_thickness.dscalar.nii
Left/Right cortical thickness anat/sub-{subid}_ses-{sesid}_hemi-{hemi}_thickness.shape.gii
Cortical thickness (curvature regressed out) anat/sub-{subid}_ses-{sesid}_desc-corr_thickness.dscalar.nii
Left/Right cortical thickness (curvature regressed out) anat/sub-{subid}_ses-{sesid}_hemi-{hemi}_desc-corr_thickness.shape.gii
Cortical myelin anat/sub-{subid}_ses-{sesid}_myelinmap.dscalar.nii
Left/Right cortical myelin anat/sub-{subid}_ses-{sesid}_hemi-{hemi}_myelinmap.shape.gii
Smoothed cortical myelin anat/sub-{subid}_ses-{sesid}_desc-smoothed_myelinmap.dscalar.nii
Left/Right smoothed cortical myelin anat/sub-{subid}_ses-{sesid}_hemi-{hemi}_desc-smoothed_myelinmap.shape.gii
Cortical regional labels projected from volume anat/sub-{subid}_ses-{sesid}_desc-drawem_dseg.dlabel.nii
Left/Right cortical regional labels projected from volume anat/sub-{subid}_ses-{sesid}_hemi-{hemi}_desc-drawem_dseg.label.gii
Left/Right Medial wall anat/sub-{subid}_ses-{sesid}_hemi-{hemi}_desc-medialwall_mask.shape.gii
Workbench file for loading surfaces anat/wb.spec
Warp from native structural space to the subject’s age respective template space xfm/sub-{subid}_ses-{sesid}_from-T2w_to-serag{age}wk_mode-image.nii.gz
Warp from the subject’s age respective template space to the native structural space xfm/sub-{subid}_ses-{sesid}_from-serag{age}wk_to-T2w_mode-image.nii.gz
Warp from native structural space to the 40-week Serag template space xfm/sub-{subid}_ses-{sesid}_from-T2w_to-serag40wk_mode-image.nii.gz
Warp from the 40-week Serag template space to the native structural space xfm/sub-{subid}_ses-{sesid}_from-serag40wk_to-T2w_mode-image.nii.gz
Transform from native surface to the dHCP Symmetric 40week surface template xfm/sub-{subid}_ses-{sesid}_hemi-{hemi}_from-native_to-dhcpSym40_dens-32k_mode-sphere.surf.gii

Diffusion EDDY pipeline

Path: derivatives/dhcp_dmri_eddy_pipeline/sub-{subid}/ses-{sesid}

Description Filename
Eddy current, susceptibility-by-motion and motion (within and between volumes) corrected super-resolved 4D volume with outlier rejection and replacement dwi/sub-{subid}_ses-{sesid}_desc-preproc_dwi.nii.gz
List of b-values dwi/sub-{subid}_ses-{sesid}_desc-preproc_dwi.bval
List of post-EDDY rotated gradient directions dwi/sub-{subid}_ses-{sesid}_desc-preproc_dwi.bvec
Brain mask dwi/sub-{subid}_ses-{sesid}_desc-brain_mask.nii.gz
Estimated field map fmap/sub-{subid}_ses-{sesid}_fieldmap.nii.gz
QC report (JSON) qc/sub-{subid}_ses-{sesid}_qc.json
QC report (PDF) qc/sub-{subid}_ses-{sesid}_qc.pdf
Rigid-body transform from structural to diffusion space xfm/sub-{subid}_ses-{sesid}_from-T2w_to-dwi_mode-image.mat
Rigid-body transform from diffusion to structural space xfm/sub-{subid}_ses-{sesid}_from-dwi_to-T2w_mode-image.mat
Warp from diffusion space to the extended dHCP 40-week template space xfm/sub-{subid}_ses-{sesid}_from-dwi_to-extdhcp40wk_mode-image.nii.gz
Warp from the extended dHCP 40-week template space to diffusion space xfm/sub-{subid}_ses-{sesid}_from-extdhcp40wk_to-dwi_mode-image.nii.gz
DTI FA map (based on b=1k shell) dwi/sub-{subid}_ses-{sesid}_model-DTI_FA.nii.gz
DTI MD map (based on b=1k shell) dwi/sub-{subid}_ses-{sesid}_model-DTI_MD.nii.gz
DTI V1 map (based on b=1k shell) dwi/sub-{subid}_ses-{sesid}_model-DTI_EVECS.nii.gz
DTI full tensor (based on b=1k shell) dwi/sub-{subid}_ses-{sesid}_model-DTI_diffmodel.nii.gz
DKI mean kurtosis map dwi/sub-{subid}_ses-{sesid}_model-DKI_MK.nii.gz

Diffusion SHARD pipeline

Path: derivatives/dhcp_dmri_shard_pipeline/sub-{subid}/ses-{sesid}

Description Filename
Topup field map fmap/sub-{subid}_ses-{sesid}_fieldmap.nii.gz
Brain mask derived from T2w, warped to preprocessed DWI dwi/sub-{subid}_ses-{sesid}_desc-brain_mask.nii.gz
Motion corrected output (5D image of multi-shell SH coefficients, x,y,z,b,m) dwi/sub-{subid}_ses-{sesid}_desc-shard_mssh.nii.gz
Motion parameters dwi/sub-{subid}_ses-{sesid}_desc-shard_motion.txt
Slice weights dwi/sub-{subid}_ses-{sesid}_desc-shard_sliceweights.txt
Local weights for fat-shift suppression dwi/sub-{subid}_ses-{sesid}_desc-shard_voxelweights.nii.gz
Preprocessed DWI data (denoising, motion correction, and destriping) dwi/sub-{subid}_ses-{sesid}_desc-preproc_dwi.nii.gz
List of b-values in FSL format dwi/sub-{subid}_ses-{sesid}_desc-preproc_dwi.bval
List of gradient directions in FSL format dwi/sub-{subid}_ses-{sesid}_desc-preproc_dwi.bvec
QC report qc/sub-{subid}_ses-{sesid}_qc.html
Rigid-body transform from structural to diffusion space xfm/sub-{subid}_ses-{sesid}_from-T2w_to-dwi_mode-image.mat
Rigid-body transform from diffusion to structural space xfm/sub-{subid}_ses-{sesid}_from-dwi_to-T2w_mode-image.mat
Warp from diffusion space to the extended dHCP 40-week template space xfm/sub-{subid}_ses-{sesid}_from-dwi_to-extdhcp40wk_mode-image.nii.gz
Warp from the extended dHCP 40-week template space to diffusion space xfm/sub-{subid}_ses-{sesid}_from-extdhcp40wk_to-dwi_mode-image.nii.gz

Functional pipeline

Path: derivatives/dhcp_fmri_pipeline/sub-{subid}/ses-{sesid}

Description Filename
Multi-band EPI, distortion corrected, motion corrected, 4D image func/sub-{subid}_ses-{sesid}_task-rest_desc-mcdc_bold.nii.gz
Multi-band EPI, distortion corrected, motion corrected, FIX denoised, 4D image func/sub-{subid}_ses-{sesid}_task-rest_desc-preproc_bold.nii.gz
Motion parameters func/sub-{subid}_ses-{sesid}_motion.tsv
Brain mask func/sub-{subid}_ses-{sesid}_task-rest_desc-brain_mask.nii.gz
Derived fieldmap, magnitude fmap/sub-{subid}_ses-{sesid}_magnitude.nii.gz
Derived fieldmap (rad/s) fmap/sub-{subid}_ses-{sesid}_fieldmap.nii.gz
QC report sub-{subid}_ses-{sesid}_funcqc.html
Rigid-body transform from functional (mcdc) to single-band Ref space xfm/sub-{subid}_ses-{sesid}_from-bold_to-sbref_mode-image.mat
Rigid-body transform from single-band Ref space to structural space xfm/sub-{subid}_ses-{sesid}_from-sbref_to-T2w_mode-image.mat
Rigid-body transform from functional (mcdc) to structural space xfm/sub-{subid}_ses-{sesid}_from-bold_to-T2w_mode-image.mat
Rigid-body transform from field-map to structural space xfm/sub-{subid}_ses-{sesid}_from-fieldmap_to-T2w_mode-image.mat
Warp from functional (mcdc) space to the extended dHCP 40-week template space xfm/sub-{subid}_ses-{sesid}_from-bold_to-extdhcp40wk_mode-image.nii.gz
Warp from the structural space to the extended dHCP 40-week template space xfm/sub-{subid}_ses-{sesid}_from-T2w_to-extdhcp40wk_mode-image.nii.gz
ICA confound regressors func/sub-{subid}_ses-{sesid}_task-rest_desc-fixregressors_timeseries.nii.gz
FOV 4D volumetric mask func/sub-{subid}_ses-{sesid}_task-rest_desc-fov4d_mask.nii.gz